WG1: LAB-SCALE SYNTHESES
WG1 will bring together experts in mechanosynthesis with the aim to design mechanochemical protocols that can offer advantages over existing solution-based methods to advance capability in this area. Furthermore, WG1 will work side by side with the other WGs in order to discover and study new types of reactivity (with WG2) and to identify suitable reactions for scaling-up (with WG3). Additionally, the direct involvement of engineers at this early stage will allow the conception of processes working at lab scale that can be realistically scaled up.
Objectives
The objectives of the WG1 will include:
- The identification of specific mechanochemical reactions (condensations, multicomponent, cascade, domino, organo- or metal-catalysed, etc.) that allow synthesising specialty products avoiding common problems arising in conventional solution routes,
- Designing the strategy to evaluate the reproducibility of specific mechanochemical reactions;
- Evaluate the effect of liquid-assisted grinding on controlling chemical reactivity and selectivity,
- Discovery of organic molecules and new compounds (CP, co-crystals, catalysts, MOFs) accessible only under mechanochemical conditions, studying their unique reactivity together with the WG2.
Milestones
- (M1) Identification of different reactions leading to compounds of industrial interest such as generic APIs, catalysts, CP and MOF for energy storage and pharmaceutical co-crystals to be investigated for the scale up process (in collaboration with WG3);
- (M2) Identify one or two benchmark reactions to understand the mechanistic aspects underlying the reactive event and the role of liquid assisted grinding in mechanochemical reactions (in collaboration with WG2);
- (M3) Identification of technical parameters allowing to optimize the reactions.
Deliverables
- Technical report on different reactions, which can be tested for scale up processess, including Guidelines, Good Practice and practical skills for mechanochemistry;
- Technical report on the achieved objectives will be presented to the annual meeting;
- Publication in leading scientific journals and open access journals.
WG1 Participants
MC MEMBER
[CA18112 EE]
MC SUBSTITUTE
[CA18112 EE]
MC MEMBER
[CA18112 PT]
ITC GRANT COORDINATOR
MC MEMBER
[CA18112 EL]
[CA18112 IT]
MC MEMBER
[CA18112 BA]
MC SUBSTITUTE
[CA18112 SK]
MC MEMBER
[CA18112 SK]
STSM GRANT COORDINATOR
MC MEMBER
[CA18112 TR]
WG1 LEADER
MC MEMBER
[CA18112 RO]
MC SUBSTITUTE
[CA18112 DE]
MC SUBSTITUTE
[CA18112 DE]
MC MEMBER
[CA18112 RS]
MC SUBSTITUTE
[CA18112 SK]
MC MEMBER
[CA18112 FR]
MC SUBSTITUTE
[CA18112 IT]
MC SUBSTITUTE
[CA18112 FR]
MC MEMBER
[CA18112 BG]
ACTION CHAIR
MC SUBSTITUTE
[CA18112 RO]
MC MEMBER
[CA18112 MK]
MC MEMBER
[CA18112 HU]
[CA18112 UK]
MC MEMBER
[CA18112 BE]
MC SUBSTITUTE
[CA18112 PT]
MC MEMBER
[CA18112 DE]
MC SUBSTITUTE
[CA18112 MK]
MC OBSERVER
[CA18112 CA]
MC MEMBER
[CA18112 CH]
MC OBSERVER
[CA18112 SG]
SCIENCE COMMUNICATION MANAGER
MC SUBSTITUTE
[CA18112 PT]
GENDER BALANCE COORDINATOR
MC OBSERVER
[CA18112 US]
MC OBSERVER
[CA18112 US]
MC MEMBER
[CA18112 MD]
MC MEMBER
[CA18112 SI]
MC OBSERVER
[CA18112 MX]
MC SUBSTITUTE
[CA18112 ME]
MC SUBSTITUTE
[CA18112 RS]
MC SUBSTITUTE
[CA18112 ME]
MC MEMBER
[CA18112 PL]
MC SUBSTITUTE
[CA18112 BE]
MC MEMBER
[CA18112 IE]
MC MEMBER
[CA18112 IT]
VICE CHAIR
[CA18112 HR]
[CA18112 IT]
MC SUBSTITUTE
[CA18112 PL]
MC MEMBER
[CA18112 PL]
ITC GRANT CO-LEADER
MC MEMBER
[CA18112 ES]
MC SUBSTITUTE
[CA18112 TR]
MC MEMBER
[CA18112 BE]
MC SUBSTITUTE
[CA18112 RS]
MC MEMBER
[CA18112 RO]
MC MEMBER
[CA18112 TR]
MC MEMBER
[CA18112 PT]
MC SUBSTITUTE
[CA18112 FR]
MC MEMBER
[CA18112 IT]
STSM GRANT CO-LEADER
MC SUBSTITUTE
[CA18112 SI]
MC MEMBER
[CA18112 ES]
SCIENCE COMMUNICATION CO-LEADER
[CA18112 IT]
[CA18112 PT]
GENDER BALANCE CO-LEADER
MC MEMBER
[CA18112 SK]
MC SUBSTITUTE
[CA18112 ME]
[CA18112 DE]
MC SUBSTITUTE
[CA18112 RO]
MC MEMBER
[CA18112 SE]
MC MEMBER
[CA18112 BA]
MC SUBSTITUTE
[CA18112 CN]
MC MEMBER
[CA18112 BA]
MC MEMBER
[CA18112 EL]
CONTACT INFO
COST
COST ACTION CA18112
COST (European Cooperation in Science and Technology) is a funding agency for research and innovation networks. Our Actions help connect research initiatives across Europe and enable scientists to grow their ideas by sharing them with their peers. This boosts their research, career and innovation